Nanoparticulate Therapies for Cancer

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Nanoparticulate ceria is a biocompatible photocatalytic material that can be designed to be resorbable in the body. It can be functionalised to facilitate uptake by diseased and damaged cells but an alternative more challenging approach is to discourage uptake by healthy cells. Once within the cells, the photocatalytic nanoparticles can be activated non-invasively by X-rays and ultrasound. With low dosages or low-efficiency photocatalyst, the cell functioning can be disrupted through the production of photocurrents. With high dosages or high-efficiency photocatalysts, the cells can be destroyed from within through the production of reactive oxygen species.

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Supervisory team
Charles
Sorrell

Science
Materials Science and Engineering
Jia-Lin
Yang

Medicine
Medicine
Pramod
Koshy

Science
Materials Science and Engineering
C.Sorrell@unsw.edu.au

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