Mechanisms of muscle contracture in children with cerebral palsy

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Children with cerebral palsy often develop muscle contractures (stiffening of muscles) that produce deformities and cause physical disability. The mechanisms that cause muscle contracture are poorly understood. It is not known with any certainty whether muscle contractures are primarily due to changes in the muscle cells or tendons.

Recently we and others have developed MRI-based methods that utilise diffusion tensor imaging to generate exquisite three-dimensional images of living human muscles. We will use these methods to investigate whether contractures in children with cerebral palsy are due primarily to changes in muscle or tendon.

Part of the project will involve development of algorithms for processing diffusion tensor images. The ideal candidate would have a background in engineering, computer science, physics, or a related discipline; experience in computer programming; and be comfortable working with children with disabilities. It is not necessary for candidates to have all of these attributes.

Supervisory team
Rob
Herbert

Medicine
NeuRA
Bart
Bolsterlee

NeuRA
Biomedical Engineering
Lynne
Bilston

NeuRA
Biomedical Engineering
Register to Apply
Non-UNSW staff/students must Register to Apply
robert.herbert@unsw.edu.au