Novel antimicrobial strategies for implantable and non-implantable devices

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Bacterial infections associated with bone grafts represent a significant public health issue, which has been exacerbated by the rapid increase of antibiotic resistance. Therefore, it is imperative to develop antimicrobial treatments that use multiple mechanisms of action in order to circumvent the development of bacterial resistance. This proposal will develop new antimicrobials technologies that provide multiple layers of protection for bone grafts without inhibiting bone healing, and act to prevent bacterial adhesion and biofilm formation. This strategy has the potential to prevent bone graft infections, reduce health care costs and advantage the biomaterials industry.

Ideally the candidate will have a Bachelors degree with First Class or Second Class/Division 1 Honours in Chemistry (or related discipline) or demonstrate equivalent research training from an Australian or overseas University, such as a Masters with a substantial thesis component. The candidate must have sound oral and written communication skills, be highly motivated, show initiative, and be capable of working with minimum supervision. They would have sound laboratory skills and a working knowledge of spectroscopic methods used for structure elucidation. Some understanding of the principles of microbiology and aseptic technique would be an advantage. The candidate will work as part of a multidisciplinary team, hence any prior exposure across disciplines will be highly regarded.

Supervisory team


Prince of Wales Clinical School