Corneal assessment as a marker of peripheral neuropathy

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Peripheral neuropathy is a highly prevalent disorder that can be due to a range of aetiologies including diabetes, chronic kidney disease and chemotherapy-induced in patients with cancer. The inability to detect early sub-clinical nerve damage has limited the development of neuroprotective agents. Corneal nerve morphology observed using in vivo corneal confocal microscopy (IVCCM) may offer predictive validity for the development and progression of neuropathy. This study will explore the utility of IVCCM as a diagnostic platform that can be used across neuropathies with a focus on type 2 diabetes, chronic kidney disease and chemotherapy-induced peripheral neuropathy.

The ideal candidate will have a background in optometry or medicine and be registered to use ophthalmic diagnostic drugs.

Supervisory team
Arun
Krishnan

Medicine
Prince of Wales Clinical School
Maria
Markoulli

Science
Optometry and Vision Science
David
Goldstein

Medicine
Prince of Wales Clinical School
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Non-UNSW staff/students must Register to Apply
arun.krishnan@unsw.edu.au