Understanding Drug Action on Malaria

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Widespread use of antimalarial drugs has significantly reduced deaths and infections from malaria over the last decade. However, resistance to most common antimalarial drugs threatens this progress. This project involves mathematical modelling of clinical and experimental data on parasite dynamics after treatment with antimalarial drugs. This will provide insight into the action of anti-malarial agents - how drugs affect parasite replication, and how the human host removes parasites from circulation. This will be used to predict the effects of novel drugs and drug combinations in controlling malaria infection.

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Supervisory team
Miles
Davenport

Medicine
The Kirby Institute
Deborah
Cromer

Medicine
The Kirby Institute
David
Khoury

Medicine
The Kirby Institute
m.davenport@unsw.edu.au

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